In addition, we assessed the quality of UWF fundus photographs that were obtained in tandem in all subjects. In this study, we sought to establish the comparative normative data for clinical use and to investigate differences in retinal thickness both in central subfoveal, as well as eight perifoveal subfields between MIIS-SD OCT and Spectralis OCT. Although OCT scans may help detect morphological alterations in the retina, in the absence of normative data, it is difficult to obtain objective quantitative comparison between scans. This unique capability of the MIIS-SD OCT reduces image acquisition time and permits improved clinic flow as both studies are completed simultaneously instead of independently. The increasing speed of data collection (A-Scan rate up to 70k cycles per second) allows enhanced resolution and better delineation of retinal layers with the assistance of built-in active eye tracking and automatic scan positioning. The Optos Monaco Integrated Imaging System Optical Coherence Tomography (MIIS-SD OCT), a novel instrument, acquires ultra-widefield (UWF) fundus photographs (200°) as well OCT images concurrently with confocal technology and obviates the need for two separate tests. In addition to OCT, fundus photographs are routine in the documentation of retinal disease and treatment course. Typically, OCT and fundus photography are performed separately. Confocal fundus cameras based on confocal imaging technology (Optos, Clarus, RetCam, Panoret) may provide a wide field of view (up to 200°). Nine-field imaging is utilized to obtain image of larger area of retina. Traditional fundus photographs (flash based) record 30–45° of the retina, and require pupillary dilation. Retinal thickness measurements in normal-appearing eyes additionally differ based on patient age, sex, ethnicity, and refractive error with older age, female gender, African American ethnicity, and degree of myopia (myopia of >5D have thinner retinal thickness measurements) ( 1, 2).įundus photographs are routinely obtained (Zeiss, Topcon) in addition to OCT in evaluation and management of retinal disorders. The retinal thickness measurements with different OCT imaging systems e.g., Heidelberg Spectralis and Zeiss Stratus has been well documented with established variations in measurement ( 1- 5). In the last decade, optical coherence tomography (OCT) has become a mainstay in providing high-resolution, quantitative measurements in retinal evaluation. Keywords: Optical coherence tomography (OCT) macular edema fundus photography retinal diseases age related macular degeneration diabetic retinopathy Integrated system provides quality fundus photographs as well as OCT, obviates the need for two separate instruments and likely improves the clinic flow. In addition, wide-angle fundus photography was successfully obtained in all subjects. An increased measurement in thickness of 35.35 µm was noted in the central fovea. Concurrently obtained ultrawide angle fundus photographs revealed (200°) clear media, normal disc, normal vasculature and normal periphery in all patients with excellent resolution.Ĭonclusions: Retinal thickness measurements strongly correlated with those obtained by Spectralis. The mean difference between retinal thicknesses was 44.88 µm (range, 21–91 µm) in the eight ETDRS subfields, with r value 0.53, P<0.05, ranging from 0.51 to 0.60. The mean CPT as measured with MIIS-SD OCT and Spectralis OCT was 268.55☒0.70 and 230.67☑7.75 µm (P<0.001) respectively. The Pearson’s correlation coefficient, r value was 0.5285, P<0.0013. Results: The mean CST as measured with MIIS-SD OCT and Spectralis OCT was 300.53☒2.81 µm and 265.18☑7.33 µm (P<0.001) respectively. Students t-test was used to determine statistical significance. Central subfield thickness (CST), central point thickness (CPT), and retinal thickness in nine central subfields were measured with both 1 instruments. ![]() All subjects underwent a complete ophthalmologic exam to ensure the absence of ocular pathology. OCT with spectralis was also obtained at the same visit for comparison. Methods: In this cross sectional study, fundus photographs and OCT was obtained concurrently in 34 eyes in healthy patients without any known retinal disease with integrated imaging system. The present study aims to measure retinal thickness and compare it to OCT obtained with traditional spectral domain OCT in subjects without known retinal disease to establish normative data for clinical use. We describe a novel integrated imaging system (Monaco, Optos) that records both OCT as well as fundus photography concurrently. Policy of Dealing with Allegations of Research Misconductīackground: Traditionally fundus photographs and optical coherence tomography (OCT) are obtained separately during evaluation of retinal pathology.Policy of Screening for Plagiarism Process.
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